‘Danger sign’: State, local government job losses grow as Congress stalls on relief

The new data undercut a Republican argument that state and local governments have gotten enough help from Washington, with some citing an uptick in revenue for many states this summer that outpaced initial projections. But the job losses suggest that economic relief that Congress approved in the CARES Act in late March gave a temporary boost to local economies that’s now drying up.

Not all Republicans have rejected more state aid outright. In an interview, Sen. Bob Menendez (D-N.J.) cited three Republican cosponsors — Sen. Bill Cassidy of Louisiana, Cindy Hyde-Smith of Mississippi and Susan Collins of Maine — for his bill to provide $500 billion in flexible grants to help state and local governments.

“One of the lessons we should take from the Great Recession was that massive layoffs and tax increases at the state and local level acted as an anchor and weighed down our economic recovery for

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Fulcrum Therapeutics Announces Multiple Presentations During the Virtual 25th International Congress of the World Muscle Society

CAMBRIDGE, Mass., Oct. 01, 2020 (GLOBE NEWSWIRE) — Fulcrum Therapeutics, Inc. (Nasdaq: FULC), a clinical-stage biopharmaceutical company focused on improving the lives of patients with genetically defined rare diseases, today announced it will present multiple posters on the company’s ongoing studies in patients with facioscapulohumeral muscular dystrophy (FSHD) during the 25th International Congress of the World Muscle Society.

“FSHD is a serious and debilitating disease for which there are currently no approved therapies,” said Diego Cadavid, MD, Fulcrum’s senior vice president, clinical development. “We are pleased to share these data at this important scientific meeting as we continue to pursue losmapimod as a potential treatment for FSHD by addressing the root cause of the disease. We greatly appreciate the patients who have participated in our trials and the support we have received from key opinion leaders and investigators.”

During the Virtual Poster Session today, October 1, 2020 from 12:30pm

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Scholar Rock Presents Data for SRK-015 at the World Muscle Society 2020 Virtual Congress

CAMBRIDGE, Mass.–(BUSINESS WIRE)–Sep 30, 2020–

Scholar Rock (NASDAQ: SRRK), a clinical-stage biopharmaceutical company focused on the treatment of serious diseases in which protein growth factors play a fundamental role, today announced two poster presentations as part of the World Muscle Society (WMS) 2020 Virtual Congress. The SRK-015 clinical development poster will showcase previously presented data from the Phase 1 healthy volunteer trial, as well as baseline characteristics and demographics from the TOPAZ Phase 2 proof-of-concept trial evaluating SRK-015 for the treatment of patients with Type 2 and Type 3 Spinal Muscular Atrophy (SMA). The second poster shares data on the pharmacologic effects of SRK-015 in patients with SMA, healthy volunteers, and across animal species.

Details for the two virtual posters at the WMS meeting are as follows:

  • Title: Clinical Development of SRK-015, a Fully Human Anti-proMyostatin Monoclonal Antibody, for the Treatment of Later-Onset Spinal Muscular Atrophy
  • Title: Myostatin
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Dynacure to Present Disease Progression Model and Natural History Study Data at the 25th Annual Congress of the World Muscle Society (WMS25)

STRASBOURG, Pa. and PHILADELPHIA, Sept. 28, 2020 /PRNewswire/ — Dynacure, a clinical stage drug development company focused on improving the lives of patients with rare and orphan disorders, announced today that the company will present two posters containing data on the natural history of Myotubular and Centronuclear Myopathies (CNM) at the 25th Annual Congress of the World Muscle Society (WMS25).  The WMS25 meeting is being held in a virtual format. 

Dynacure is developing DYN101, an investigational antisense medicine designed to modulate the expression of dynamin 2 (DNM2), for the treatment of CNM.  DYN101 is currently being evaluated in a Phase 1/2 clinical study, ‘UNITE-CNM’ (DYN101-C101), at multiple clinical sites in Europe. 

Details of the poster presentations are listed below:

Poster Abstract: # LSP (late submitted poster) 6
Title: Hierarchical Bayesian model of disease progression in centronuclear myopathy allows to demonstrate treatment efficacy with a small sample size
Date: Thursday,

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Exelixis to Host Investor Briefing to Discuss Data Presented at the European Society for Medical Oncology Virtual Congress 2020

ALAMEDA, Calif.–(BUSINESS WIRE)–Exelixis, Inc. (Nasdaq: EXEL) today announced it will host an investor briefing to discuss data presented at the European Society for Medical Oncology (ESMO) Virtual Congress 2020. The online-only event will be held following the closing of the Congress’ sessions on Saturday, September 19, 2020, beginning at 22:00 (10:00 p.m.) CEST / 4:00 p.m. EDT / 1:00 p.m. PDT.

During the briefing, Exelixis management and invited guests from the clinical community will discuss and provide context for the cabozantinib clinical data presented at the Congress. Exelixis previously announced that detailed results from CheckMate -9ER, the phase 3 pivotal trial evaluating CABOMETYX® (cabozantinib) in combination with Opdivo® (nivolumab) compared with sunitinib in previously untreated patients with advanced or metastatic renal cell carcinoma, will be presented during the Congress’ Presidential Symposium I earlier in the day. The investor briefing will also review data from COSMIC-021, the

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Americans Were Offered Out For Cash, Energy And Greed By Congress

Government Grants can assist you in case you are trying to eliminate your debt and have extra financial freedom in your life. When you examine Obama’s speech, it seems Obama needs retroactive energy to incarcerate anyone government claims (prior) supported violent acts on the premise, that particular person is prone to interact in violent acts in the future: U.S. activists can be vulnerable as a result of no activist can control what different activists or teams might do illegally they community with domestically or abroad.

Corruption in elections and in legislative bodies reduces accountability and distorts illustration in policymaking; corruption within the judiciary compromises the rule of legislation; and corruption in public administration results in the inefficient provision of companies.

Most individuals compare public administration to enterprise administration and the Master in this subject are compared to a Grasp in Business Administration. Learn how much cash U.S. Congress members will … Read More

Can Members Of Our U.S. Congress Retire With Full Pay After Simply One Term? The

During these financial hardships, individuals should take advantage of every opportunity in making their life secure. The Declaration of Independence boldly states that each citizen has an unalienable right to life, liberty, and the pursuit of happiness (). Although lots of our government’s restrictions and impositions could be construed as violating these most simple of rights, and although the supreme court docket tries to not acknowledge the DOI’s authority as the first regulation of the land, the Structure states comparable protections so far as the government’s interference in it’s citizens freedoms.

If we do nothing and not let our government know that we’re smart informed People, who won’t let our Nation be sold out for Cash, Power and Greed. Quoting the statement from Transparency Worldwide of how the corrupt leadership of Gaddafi has precipitated a disaster within the nation The oil-wealthy country is on the verge of changing into a … Read More