Bayer to Present Results From Phase III FIDELIO-DKD Study with Finerenone in Patients with Chronic Kidney Disease and Type 2 Diabetes during Late-Breaker Session at the American Society of Nephrology’s Kidney Week 2020

WHIPPANY, N.J.–(BUSINESS WIRE)–Bayer will present detailed results from the Phase III FIDELIO-DKD study assessing the use of the investigational drug finerenone on kidney and cardiovascular outcomes in patients with chronic kidney disease (CKD) and type 2 diabetes (T2D) during scientific sessions of the upcoming American Society of Nephrology’s (ASN) Kidney Week, October 22-25, 2020. Additional data evaluating use of finerenone will also be presented.

The FIDELIO-DKD study, which evaluated the efficacy and safety of finerenone versus placebo when added to standard of care in patients with CKD and T2D, is the first large contemporary positive outcomes study in patients with CKD and T2D with a primary composite endpoint exclusively consisting of kidney-specific outcomes. Bayer announced earlier this year that FIDELIO-DKD met its composite primary renal endpoint and its composite key secondary cardiovascular endpoint.

Full data from the FIDELIO-DKD study will be presented as part of the live-streamed, late-breaker

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Tricida Announces Twelve Data Presentations on Veverimer and Metabolic Acidosis to be Given at the Virtual American Society of Nephrology Kidney Week 2020

SOUTH SAN FRANCISCO, Calif.–(BUSINESS WIRE)–Tricida, Inc. (Nasdaq: TCDA), a pharmaceutical company focused on the development and commercialization of its investigational drug candidate, veverimer (TRC101), a non-absorbed, orally-administered polymer designed to treat metabolic acidosis in patients with chronic kidney disease (CKD), announced today that it has authored or sponsored 12 presentations at the upcoming American Society of Nephrology (ASN) Kidney Week 2020 being held virtually October 22-25, 2020. Data to be presented at multiple sessions at the meeting will expand the breadth of information about the implications of metabolic acidosis and CKD. All Tricida presentations will be available on Thursday, October 22, 2020 at 10:00am ET. Session and presentation titles are listed below:

Session Title: CKD Risk Factors: Diet, Environment, Lifestyle

Title:

Relationship Between Metabolic Acidosis and Chronic Kidney Disease Progression is Evident Across United States Racial and Ethnic Groups

Author:

N. Tangri et al.

ePoster #:

PO0468

 

 

Title:

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Valentine is Your Rancho Coastal Humane Society Pet of The Week

This post was contributed by a community member. The views expressed here are the author’s own.

Valentine is pet of the week at your Rancho Coastal Humane Society. He’s an 8-month-old, 12- pound, male, Domestic Short Hair cat with a Brown Tabby coat.

Valentine was a two-month-old kitten when he was taken to another shelter. After that he was transferred to Rancho Coastal Humane Society through the FOCAS (Friends of County Animal Shelters) program. He spent a few weeks in foster care before returning to Rancho Coastal Humane Society, where he was quickly adopted.

Five months later, his adopter returned Valentine, saying that he was too active for their home situation.

Valentine is still very much a kitten. He’s outgoing and social with people. He might do best in a home where the owners have had cats in the past.

The $100 adoption fee for Valentine includes medical exams,

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Dicerna to Present Nedosiran Data at American Society of Nephrology (ASN) Kidney Week 2020

Dicerna Pharmaceuticals, Inc. (Nasdaq: DRNA) (the “Company” or “Dicerna”), a leading developer of investigational ribonucleic acid interference (RNAi) therapeutics, today announced that clinical data on nedosiran, an investigational candidate for the treatment of primary hyperoxaluria (PH), will be presented during the American Society of Nephrology (ASN) Kidney Week taking place Oct. 22-25, 2020. In addition, a commercial claims analysis of clinical and economic burden associated with PH will also be presented.

The following poster presentations will be available during the “Genetic Diseases of the Kidneys: Non-Cystic – 1” session taking place on Thursday, Oct. 22, 2020 at 10:00 a.m. ET:

  • Title: PHYOX™3: A Long-Term, Open-Label Extension Trial of Nedosiran in Patients With Primary Hyperoxaluria Type 1, 2 or 3
    Poster #: PO1625

About Primary Hyperoxaluria

Primary hyperoxaluria (PH) is a family of ultra-rare, life-threatening genetic disorders that initially manifest with complications in the kidneys. There are three known types of

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Pound falls on reports UK could quit Brexit talks next week

Britain's Prime Minister Boris Johnson as fears grow Brexit talks could collapse. Photo: Justin Tallis/AFP via Getty Images
Britain’s Prime Minister Boris Johnson as fears grow Brexit talks could collapse. Photo: Justin Tallis/AFP via Getty Images

The pound slid on Wednesday, after a report that the UK government could pull out of Brexit talks as soon as next week if not enough progress has been made towards a deal.

Sterling had lost 0.8% against the dollar (GBPUSD=X) by mid-afternoon in the UK, trading just below $1.29. It shed 0.7% against the euro (GBPEUR=X), with the pound selling for $1.09.

The flight from sterling reflects investors fears’ Britain could face severe economic upheaval if no deal is reached. It would likely spark disruption and sudden new barriers to long-standing trade and other ties with most of Europe when the Brexit transition period expires at the end of the year.

Talks between negotiators are ongoing in London this week. The pound’s decline came after a source told Bloomberg the UK

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Lebanon’s President Says Consultations on New Government Start Next Week | World News

BEIRUT (Reuters) – Lebanon’s President Michel Aoun said on Wednesday parliamentary consultations to choose a new prime minister who will form the country’s next government will begin on Oct. 15.

Lebanon’s government resigned on Aug. 10 in the wake of a devastating blast that killed nearly 200 people and wrecked swathes of the capital, Beirut.

Mustapha Adib, the country’s former ambassador to Berlin, was picked on Aug. 31 to form a cabinet after French President Emmanuel Macron intervened, securing a consensus on naming him in a country where power is shared out between Muslim and Christian sects.

He quit in late September, however, after trying for almost a month to line up a non-partisan cabinet. His resignation dealt a blow to a French plan aimed at rallying sectarian political leaders to tackle the worst crisis since the nation’s 1975-1990 civil war.

Under the French roadmap, the new government would take

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Lebanon’s president says consultations on new government start next week

BEIRUT (Reuters) – Lebanon’s President Michel Aoun said on Wednesday parliamentary consultations to choose a new prime minister who will form the country’s next government will begin on Oct. 15.

Lebanon’s government resigned on Aug. 10 in the wake of a devastating blast that killed nearly 200 people and wrecked swathes of the capital, Beirut.

Mustapha Adib, the country’s former ambassador to Berlin, was picked on Aug. 31 to form a cabinet after French President Emmanuel Macron intervened, securing a consensus on naming him in a country where power is shared out between Muslim and Christian sects.

He quit in late September, however, after trying for almost a month to line up a non-partisan cabinet. His resignation dealt a blow to a French plan aimed at rallying sectarian political leaders to tackle the worst crisis since the nation’s 1975-1990 civil war.

Under the French roadmap, the new government would take

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New Michigan law lets ballot processing start early, but don’t expect results until Friday of election week

Michigan officials expect record-breaking turnout for the Nov. 3 election and Gov. Gretchen Whitmer has signed a few last-minute bills into law to speed the process and ensure every ballot is counted.

On Tuesday, Whitmer signed Senate Bill 757, passed by the House and Senate in September, to allow clerks in cities and townships with at least 25,000 people to start processing absentee ballots Nov. 2. The ballots can’t be tabulated until 7 a.m. on election day, however.

While the move is a “step in the right direction” per Secretary of State Jocelyn Benson, it’s not enough, she said. States like Kentucky, Ohio, North Carolina and Florida allow more time for processing – sometime weeks more, Benson said.

The change won’t significantly alter when the results will be ready, Benson said.

“We still expect that it will be the Friday of election week that we expect every ballot will be

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Fluorine is Your Rancho Coastal Humane Society Pet of The Week

This post was contributed by a community member. The views expressed here are the author’s own.

Fluorine is pet of the week at your Rancho Coastal Humane Society. She’s a 1 year old, 53 pound, female, Husky mix.

Fluorine was a stray in the Imperial Valley when she and her brother were picked up with two other dogs. They went to a local animal shelter then transferred to Rancho Coastal Humane Society through the FOCAS (Friends of County Animal Shelters) program.

Fluorine’s brother was adopted. Now she needs a new home.

She’s timid. Her new family will need to help her build confidence as she settles into her new home. She might like living with another dog.

The $145 adoption fee for Fluorine includes medical exams, vaccinations, spay, registered microchip, and a one-year license if her new home is in the jurisdiction controlled by San Diego Humane Society’s Department

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Medeor Therapeutics Announces Data Presentation at the American Society of Nephrology Kidney Week 2020

Medeor Therapeutics, Inc., a clinical-stage biotechnology company dedicated to improving the lives of transplant patients by a unique immunotherapeutic approach, today announced that interim results from the company’s MERCURY Phase 3 clinical trial will be presented by lead Principal Investigator Dr. Dixon Kaufman of the University of Wisconsin at the American Society of Nephrology (ASN) Kidney Week 2020, being held virtually from October 19-25, 2020. The presentation will review the safety and efficacy of cellular immunotherapy with MDR-101 for induction of functional immune tolerance in recipients of human leukocyte antigen (HLA)-matched, living donor kidney transplants.

Details of the oral presentation are as follows:
Title:
Interim Update of the MDR-101-MLK Phase 3 Trial – MERCURY STUDY
Session Number: Oral Abstract Session – 1901
Session Title: In-Depth Look at Transplantation: Basic and Translational
Date/ Time: Friday, October 23, 5:00pm-7:00pm ET

MDR-101 is intended to induce donor specific immune tolerance in order to

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